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Human Research Protection Program

Center for Creative Education BuildingUniversity of Toledo sign at campus entranceresearchers in a lab with gown and masks onmain campus in the fall aerial view in the fallUTMC building in Spring

Welcome to the Human Research Protection Program & Institutional Review Boards

The HRPP provides guidance to researchers and administrative support for the Biomedical and Social Behavioral & Educational Institutional Review Boards.

The University of Toledo affirms the need for academic freedom in the conduct of research and the value of well-designed, responsible activities that involve human subjects. At the same time it recognizes the basic responsibility to assure the protection of any human subjects and has established the Human Research Protection Program (HRPP) to oversee that responsibility.Ìý The HRPP provides guidance to researchers and administrative support for the Biomedical and Social Behavioral and Educational Institutional Review Boards.

Basic Principles

Investigations conducted at The University of Toledo are expected to embody the following basic principles in agreement withÌý, Ìý,ÌýThe University of Toledo’s Federal wide Assurance for Protection of Human Subjects and the “ 45 CFR 46, Subpart A: and 45 CFR 46 Subparts B, C and D.

  1. Participation of human beings as subjects must be voluntary, i.e., must occur as a result of free choice, without compulsion or obligation, based upon disclosure of relevant information in a comprehensible way.

  2. Adequate standards of informed consent must always be utilized.

  3. Adequate provision must be made to protect the privacy of subjects and maintain the confidentiality of information.

  4. The selection of subjects must be based upon fair procedures and not overburden, over-utilize, or unfairly favor, or discriminate against, any particular subject pool.
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  5. Any risks to the subject must be carefully minimized, and adequately balanced against potential benefits. Proper precaution should be taken and plans made to deal with emergencies that may develop in the course of even seemingly routine activities. Ìý

  6. Approval for any human subject research must be obtained from one of the ¹û¶³´«Ã½ IRBs prior to the initiation of any research activities.
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